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NAD+ and addiction: a critical examination of a pilot study involving fifty cases

Study design: Humans; uncontrolled pilot study with 50 cases

The research question

There is research in which NAD+ appears in the context of substance-use problems. The question is which intervention was actually tested and whether the changes can be attributed to NAD+ itself.

What was found?

This pilot describes fifty cases involving an infusion intervention that combined NAD+ with enkephalinase inhibition. The authors reported improvements in craving and psychological symptoms. The study had no randomized control group and did not test an isolated NAD+ intervention.

What does this evidence mean?

A change before and after treatment does not show which component was responsible. Counseling, other components of the intervention, and time may have played a role. The publication is a preliminary signal, not evidence that NAD+ infusions independently treat addiction or produce lasting recovery.

Primary source

PubMed — PMID 36118157

Research information, not treatment advice. The study described does not establish the safe use of an investigational product. Image: AI illustration, not a participant or a photograph from the study.

Related research products

View product specifications and available batch documentation. The studies discussed were not conducted with Peptidera products and do not prove the efficacy of our products. For laboratory research only; not for human or animal consumption.

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