LL-37 in venous leg ulcers: two clinical studies side by side
This Research Library page summarizes independently published research on LL-37. For each study, the research model, key finding, and main limitation are stated.
Study 1
Evidence level: Human research - RCT
Subject: Topical LL-37 for hard-to-heal venous leg ulcers.
Key finding: The study reported a dose-related signal for wound healing and assessed safety.
Main limitation: Specific topical drug formulation and wound type; not generalizable to systemic use.
Source: Original publication via PubMed
Study 2
Evidence level: Human research - phase 2b RCT
Subject: Topical LL-37 plus compression therapy.
Key finding: No significant difference in wound healing compared with placebo was found in the overall study population.
Main limitation: More neutral follow-up result; should be presented together with the earlier positive dose-study result.
Source: Original publication via PubMed
Scientific scope: Research on a molecule, research model, or pharmaceutical formulation does not constitute evidence for the efficacy, safety, purity, or suitability of a commercial Peptidera product. This page does not provide treatment or usage advice.
Header image: illustrative visualization, not a research result.
Related research products
View product specifications and available batch documentation. The studies discussed were not conducted with Peptidera products and do not prove the efficacy of our products. For laboratory research only; not for human or animal consumption.