AED in aging skin fibroblasts: study of cellular markers
Evidence level: Cell research: skin fibroblasts during aging in culture · Publication year: 2016
This overview discusses one original scientific publication on Cartalax / AED. The source is included in PubMed, the literature database of the U.S. National Library of Medicine.
What was studied?
Researchers compared KE, KED, AED, and AEDG for markers of proliferation, apoptosis, and extracellular matrix degradation. AED is the peptide variant generally associated with the Cartalax research line.
What did the researchers find?
The peptides studied reduced MMP-9 and increased Ki-67 and CD98hc. AED and AEDG also reduced caspase-dependent apoptosis in this model.
What are the limitations?
The study involved skin fibroblasts, not patients with joint complaints. The results do not prove cartilage repair or rejuvenation. To link the findings to a product, the exact peptide identity must match.
Significance for research
This publication makes the bioregulator literature more concrete by identifying individual cellular markers.
Official source
Original publication via PubMed — PMID 27259496 · DOI: 10.1007/s10517-016-3370-x
Research Use Only. This literature summary contains no treatment or usage advice. Research on a molecule is not evidence of the efficacy, safety, or purity of a Peptidera product. PubMed indexing is not product approval.
Related research products
View product specifications and available batch documentation. The studies discussed were not conducted with Peptidera products and do not prove the efficacy of our products. For laboratory research only; not for human or animal consumption.