MOTS-c, exercise, and muscle homeostasis: what was actually measured?
Evidence level: Cell and animal research, with human exercise measurements · Publication year: 2021
This overview discusses one original scientific publication on MOTS-c. The source is included in PubMed, the literature database of the U.S. National Library of Medicine.
What was studied?
The researchers combined muscle cell models, experiments in mice, and exercise-related measurements in humans. They investigated the relationship between MOTS-c, metabolic adaptation, and physical performance.
What did the researchers find?
The study reported adaptation of muscle cell processes and improved performance measures in treated mice. In humans, endogenous MOTS-c measurements changed around exercise.
What are the limitations?
The human measurements are not an intervention trial in which people received MOTS-c. An increase in an endogenous peptide during exercise does not prove a benefit of a research product.
Significance for research
The different components should be read separately: intervention in mice and physiological measurements in humans provide different types of evidence.
Official source
Original publication via PubMed — PMID 33473109
Research Use Only. This literature summary contains no treatment or usage advice. Research on a molecule is not evidence of the efficacy, safety, or purity of a Peptidera product. PubMed indexing is not product approval.
Related research products
View product specifications and available batch documentation. The studies discussed were not conducted using Peptidera products and do not prove the efficacy of our products. For laboratory research only; not for human or animal consumption.